Hydrotik has posted quite a comprehensive list of resources and must-have-utilities for 2009. I’ve picked a few of my own favorites that I’ll definitely will use or play with during 2009.
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Popforge
Popforge AS3 audio library allows you to create a valid flash.media.Sound object with your own samples. This opens up new perspectives for sound design with the current Adobe Flash Player 9. You can create synthesizers, effects and sample-players of any kind. The supplied AudioBuffer class allows you to create endless audio playback. - Prana
Prana is an Inversion of Control (IoC) Container for ActionScript 3.0, and more specifically the Flex framework. It enables you to configure objects and components in a non-intrusive way by describing them in an external xml document and having them loaded at runtime. - GO
The Go !ActionScript Animation Platform is a lightweight, portable set of generic base classes for buliding your own AS3 animation tools. A few community projects can be found at Goplayground. - FLARToolKit
The augmented reality experiment, of which I posted a video about earlier this year - Papervision3D And Real Work Interaction